Idiopathic nephrotic syndrome in South African children.
نویسندگان
چکیده
منابع مشابه
Idiopathic nephrotic syndrome in Iranian children.
Of 231 children with nephrotic syndrome, 87% were steroid sensitive and 13% steroid resistant. Of patients with steroid sensitive nephrotic syndrome, 38.8% were non-relapsers, 34.8% frequent relapsers and 26.4% infrequent relapsers. Among those with steroid resistant nephrotic syndrome, 37.5% had focal segmental glomerulosclerosis with a high mortality rate of 44%
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BACKGROUND Nephrotic patients are prone to atherosclerosis in consequence of frequent exposures to hyperlipidemia, hypertension, and immunosuppressive drugs. OBJECTIVES We studied the carotid parameters as early indicators of atherosclerosis in children with nephrotic syndrome. METHODS Between 2008 and 2011, 51 children with history of nephrotic syndrome enrolled in the study. The inclusion...
متن کاملMetabolic Bone Disease in Children with Idiopathic Nephrotic Syndrome
Children with idiopathic nephrotic syndrome (INS) may be at risk for metabolic bone disease (MBD) because of biochemical derangements caused by the renal disease, as well as the corticosteroid effects on bone. We studied 70 children with INS for clinical, biochemical, and radiological evidence of MBD. These patients were divided into two groups: 55 frequent relapsers (FR; group I), and 15 infre...
متن کاملBone mineral density in children with idiopathic nephrotic syndrome.
OBJECTIVES To assess bone mineral density (BMD) in children with idiopathic nephrotic syndrome (NS) and normal glomerular filtration rate (GFR). METHODS Cross-sectional case-control study carried out on 50 children: 25 cases of NS (16 steroid-sensitive [SSNS] and nine steroid-resistant [SRNS] under follow up in the pediatric nephrology unit of Menoufia University Hospital, which is tertiary c...
متن کاملAnti-CD20 Antibodies for Idiopathic Nephrotic Syndrome in Children.
Rituximab, a chimeric anti-CD20 monoclonal antibody originally licensed for lymphoma, is emerging as a novel steroid-sparing agent for idiopathic nephrotic syndrome in children. The potential use of anti-CD20 monoclonal antibodies in idiopathic nephrotic syndrome has contributed to shifting the view of podocytopathies from T cell-mediated to more complex immunomediated disorders that can benefi...
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ژورنال
عنوان ژورنال: African Health Sciences
سال: 2018
ISSN: 1680-6905
DOI: 10.4314/ahs.v17i4.22